A Luxembourg SME has developed a unique, fast and efficient biomolecule (e.g. antibodies, antigens) deposition technology, and seeks partnership with Enzyme Linked ImmunoSorbent Assay (ELISA) kit manufacturers to bring it to the market. Commercial agreement with technical assistance is sought.
Coated ELISA kits typically consist of a 96-well strip plate pre-coated with capture antibody made under wet-chemical conditions. The Luxembourg-based SME has developed a unique plasma-based technology which allows to functionalize diverse substrates with sensitive (bio)chemistry. The technology allows 1-step deposition of a wide range of chemistries, including labile organics and biomolecules. Due to a proprietary design, the plasma is very gentle, thereby preserving substrate and (bio)chemistry functionality. This technology was applied to deposit a full fragment antibody (IgG) onto an inert substrate in a 1-step 10 second process, with fully preserved functionality as confirmed by ELISA. The deposition was comparable in efficiency to a reference wet-chemical process. This process was performed in 96 well microwell plates, with good reproducibility. The company, active in engineering and manufacturing of industrialized plasma equipment, is looking to partner with Enzyme Linked ImmunoSorbent Assay (ELISA) kit manufacturers to evaluate/ further develop/ bring to market this novel technology. Commercial agreement with technical assistance is sought.
Type (e.g. company, R&D institution…), field of industry and Role of Partner Sought:
- Type of partner sought: Large company or SME - Specific area of activity of the partner: Enzyme Linked ImmunoSorbent Assay (ELISA) kit development and manufacture - Task to be performed: validate the deposition technology and the functionality of the deposed biomolecules, implementation the technology into the fabrication process of ELISA kit and scale-up
Stage of Development:
Available for demonstration
Comments Regarding Stage of Development:
Proof of concept of 1-step antibody deposition performed and validated with university of KU Leuven, Belgium.
Granted patent or patent application essential