BACKGROUND Many drugs contain fluorinated functional groups in order to add advantageous properties. Fluorinated functional groups are more likely to withstand metabolic oxidation and, thus, are less prone to rapid degradation. The fluorination also increases the lipophilicity, which is one of the tuning factors for the bioavailability of the drug. A common approach is the fluorination of the methyl group (CH3) to trifluoromethyl (CF3). Related groups like the pentafluorosulfanyl (SF5) group have additional benefits because of their size and hydrolytic stability.

A Swiss spin-off from a University of Applied Sciences has developed an electric vehicle specifically designed for urban, short distance mobility. The vehicle helps to reduce the inner-city CO2-emissions caused by traffic. It is extremely easy and fun, as well as safe to drive in all weather conditions and also on slippery floors. The vehicle has a maximum speed of 45 km/h. It has the smallest footprint (1.2m2) and is the lightest (80 kg) three-wheel vehicle on the market.

BACKGROUND: The non-Typhoidal Salmonella (NTS) serotypes are a primary cause of foodborne illnesses worldwide. As well as causing infections, these bacteria are very often asymptomatically carried in the intestinal microbiota of livestock, which is a major concern in pigs and chickens. The main preventive measures currently are hygiene practices such as handwashing, safe food preparation, quarantine, as well as antibiotics treatment.

The home care business faces two fundamental problems, a huge load of administration work and the predictability and availability of care resources. A Swiss e-health SME develops two digital products under two companies to relieve this pain. Both products were tested in the founders own home care organisation in everyday use and were continuously improved. 1. Administration pain The ambulatory care process is regulated and requires a lot of administration. Existing software is complex and often too expensive.